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Cosmatic and Health: Informationon Cosmatic and Health

Millions of women and men around the world use cosmetics to improve or change their appearance. The general term makeup refers to cosmetics such as foundation, eyeshadow, eyeliner, mascara, blush, and lipstick. Other beauty products may include manicures, body washes and moisturizers, perfumes, and hair dyes or styling products.

There are several chemical reactions associated with hair dyes and straighteners. For example, permanent hair dye is mixed with colorless dye precursors and stabilizers and applied to the scalp and hair. Chemical processes mix together to create the final color to bind the hair.

The Federal Food, Drug, and Cosmetics Act require U.S. manufacturers to report the safety of their cosmetics to the U.S. Food and Drug Administration. But cosmetics do not pass strict pre-approval as a medicine except for color additives.1 Make-up product containing sunscreen are treated as cosmetics and medicines.

Cosmetics and toiletries contain chemicals. Researchers are working to better understand which of these affects human health. Some chemicals are classified as endocrine disruptors, which means that they can interfere with the body's hormones and adversely affect health.2

What does Niesu do?
Chemical Testing of cosmetics and Personal Care Products-The National Toxicology Program conducts research on chemicals used in cosmetics and personal care products, such as::
Antimicrobial agents, such as triclosan, are used in somebody washes and other products to kill microorganisms, such as bacteria, or stop their growth.
Engineered nanomaterials such as zinc oxide and titanium dioxide are commonly used in cosmetics and sunscreens to protect the skin from harmful UV rays. Engineered nanomaterials are measured in nanometers. The nanometer is one millionth of a millimeter, about 100,000 times smaller than the diameter of a human hair.
Parabens are used to maintain the shelf life of many cosmetic and personal care products.
Phthalates are found in cosmetics and plastic packaging, such as nail polish and hairspray.
Ultraviolet (UV)filters, compounds that protect the skin or limit the decomposition of substances from harmful sun exposure,are commonly used in sunscreens and other cosmetics, some toys, plastic products, and furniture finishes.

UV filters are of public health interest because millions of people use products made with them. Sun exposure to ultraviolet radiation is a risk factor for skin cancer. Other cosmetics, including sunscreen and UV filters, are applied to the skin, but decomposition chemicals are found in the urine, suggesting that UV filter chemicals enter the body. People can also come across these chemicals by touching products made with them or eating foods that touch UV filters and plastics.

Ultraviolet filters are studied by assessing hormonal activity, reproduction and growth and development of offspring. This type of filter includes the following features: 2-hydroxy-4-methoxybenzone, avobenzone,ensulizol,novosalate,padimate-O,octyl methoxycinnamate, octyl salad and octocrylene.
Nisus Sister Study-Using data from the Niesus Sister study, Niesus researchers found that women who showered had an increased risk of ovarian cancer.3 The study also found that among white women, those classified as medium and heavy users of beauty products had an increased risk of breast cancer compared to those who rarely used them. People who frequently used skin care products had an increased risk of breast cancer compared to those who rarely used them,and among black women, the number of participants in the subcategory of product use was too small to draw conclusive conclusions.4

When analyzing the use of hair products,researchers found that excessive use of permanent hair dyes was associated with an increased risk of developing cancer,especially in women with dark skin. Heavy use of chemical hair straighteners has also been associated with an increased risk of breast cancer, regardless of race.5

In a separate study, the researchers analyzed data from a sister study and three other prospective cohort studies on genital powder and ovarian cancer use. There was no statistically significant association between genital powder use and ovarian cancer,but there was a slight increased risk of ovarian cancer in women whose reproductive health was not compromised(no hysterectomy or tubal ligation).6
A study funded by salon workers and pregnancy-Nies found that women who worked as hairdressers and manicurists had an increased risk of developing gestational diabetes, a type of diabetes that occurs during pregnancy. They also found a higher risk of transposing placenta, a condition in which the placenta partially or completely covers the cervix.This condition can cause severe bleeding during pregnancy and childbirth.7
Adolescent and Endocrine Disruptors-NIES-supported studies have shown that Latino girls who reported daily use of personal care products had more endocrine disruptors chemicals in their urine that can affect reproductive development.8
Cooperation with other federal agencies


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